2009

Publications:

• Arendt-Nielsen L, Olesen AE, Staahl C, Menzaghi F,Kell S, Wong G, Drewes AM. Analgesic Efficacy of Peripheral kappa-Opioid receptor agonist CR665 compared to Oxycodone in a multi-modal, multi-tissue experimental human pain model: selective efekt on visceral pain. Anesthesiology 2009;111(3):616-624.
• Arendt-Nielsen L, Drewes AM. Understanding drug interaction in the gut. Paineurope 2009;1:4-5
• Baumont H, Gondrie JJ, McMahon BP, Pouw RE, Gregersen H, Bergman JJ, Boeckxstaens GE. Stepwise radiofrequency ablation of Barrett's esophagus preserves esophageal inner diameter, compliance and motility. Endoscopy 2009;41(1):2-8
• Brock C, Andresen T, Frøkjær JB, Gale J, Olesen AE, Arendt-Nielsen L, Drewes AM.  Central pain mechanisms following combined acid and capsaicin perfusion of the human oesophagus. European Journal of Pain, 2009.
• Brock C, Arendt-Nielsen L, Wilder-Smith O, Drewes AM. Sensory testing of the human gastrointestinal tract. World Journal of Gastroenterology 2009;15(2):151-159.
• Chen P, Zhao JB, Nielsen VH, Clausen T, Gregersen H. Intestinal remodelling in mink fed with reduced protein content. Journal of Biomechanics 2009;42(4):443-448
• Detlefsen S, Drewes AM. Autoimmune pancreatitis. Scand J Gastroenterol 2009;44(12):1391-407
• Detlefsen S, Drewes AM, Vyberg M, Klöppel G. Diagnosis of autoimmune pancreatitis by core needle biopsy: application of six microscopic criteria. Virchows Arch 2009;454(5):531-539.
• Drewes AM. Nye metoder til evaluering af sensoriske, biomekaniske og motoriske funktioner i mave-tarm-kanalen [Novel methods for the assessment of sensory, biomechanical and motor functions of the gastrointestinalt tract]. Ugeskrift for Læger 2009;171(141):1178-1182
• Frøkjær JB, Drewes AM, Gregersen H.  Imaging of the gastrointestinal tract-novel technologies. World Journal of Gastroenterology 2009;15(2):160-168
• Frøkjær JB, Søfteland E, Graversen C, Dimcevski G, Egsgaard LL, Arendt-Nielsen L, Drewes AM. Central processing of gut pain in diabetes patients with gastrointestinal symptoms. Diabetes Care 2009;32(7):1274-1277
• Gao F, Liao D, Drewes AM, Gregersen H. Modelling the elastin, collagen and smooth muscle contribution to the duodenal mechanical behaviour in patients with systemic sclerosis. Neurogastroenterology and Motility 2009;21(9):914
• Gazerani P, Pedersen NS, Drewes AM, Arendt-Nielsen L. Butolinum toxin type A reduces histamine-induced itch and vasomotor responses in human skin. Br J Dermatol 2009;161(4):737-45
• Gazerani P, Pedersen NS, Staahl C, Drewes AM, Arendt-Nielsen L. Subcutaneous Botulinum toxin type A reduces capsaicin-induced trigeminal pain and vasomotor reactions in human skin. Pain 2009;141:60-69
• Gravesen F, Funch-Jensen P, Gregersen H, Drewes AM. Axial force measurement for esophageal function testing. World Journal of Gastroenterology 2009; 15(2):139-143
• Gravesen FH, Gregersen H, Arendt-Nielsen L, Drewes AM. Reproducibility of axial force and manometric recordings in the oesophagus during wet and dry swallows.Neurogastroenterology and Motility, 2009 [e-pub]
• Hennings K, Lelic D, Petrini L. An automated method for micro-state segmentation of evoked potentials. Journal of neuroscience methods 2009;177(1):225-231
• Hoff D, Gregersen H, Hatlebakk JG. Mucosal blood flow measurements using laser Doppler perfusion monitoring. World Journal of Gastroenterology 2009;15(2):198-203
• Hoff D, Gregersen H, Odegaard S, Liao D, Hatlebakk J. Mechanosensation and Mucosal Blood Perfusion in the Esophagus of Healthy Volunteers Studied with a Multimodal Device Incorporating Laser Doppler Flowmetry and Endosonography. Digestive Diseases and Sciences, 2009 [e-pub]
• Krarup AL, Villadsen GE, Mejlgaard E, Olesen SS, Drewes AM, Funch-Jensen P. Acid hypersensitivity in patients with eosinophilic oesophagitis. Scandinavian Journal of Gastroenterology 2009.
• Lelic D, Gratkowski M, Valeriani M, Arendt-Nielsen L, Drewes AM. Inverse modeling  on decomposed electroencephalographic data: A way forward? Journal of Clinical Neurophysiology 2009;26(4):227-235
• Liao D, Zhao J, Kunwald P, Gregersen H. Tissue softening of guinea pig oesophagus tested by the tri-axial test machine. Journal of Biomechanics 2009;42(7):804-810
• Liao D, Zhao JB, Gregersen H. Gastrointestinal tract modelling in health and disease. World Journal of Gastroenterology 2009;15(2):169-176
• McMahon B, Jobe B, Pandolfino J, Gregersen H. Do we really understand the role of the oesophagogastric junction in disease? World Journal of Gastroenterology 2009;15(2):114-150
• Natali AN, Carniel EL, Gregersen H. Biomechanical behaviour of oesophageal tissues: Material and structural configuration, experimental data and constitutive analysis. Medical Engineering & Physics. 2009 [e-pub
• Olesen AE, Andresen T, Christrup L, Upton R.  Translational pain research: Evaluating analgesic effect in experimental visceral pain models. World Journal of Gastroenterology 2009;15(2):177-181
• Olesen AE, Staahl C, Brock C, Arendt-Nielsen L, Drewes AM. Evoked human oesophageal hyperalgesia: A potential tool for analgesic evaluation? Basic & Clinical Pharmacology & Toxicology 2009;105(2):126-136
• Olsen SS, Krarup AL, Brock C, Drewes AM. Gastrointestinal sensations and pain: a review on basic, experimental and clinical findings. Minerva Gastroenterol Dietol 2009;55(3):301-14
• Olesen SS, Olesen AE, Gravesen F, Poulsen JL, Funch-Jensen P, Gregersen H, Drewes AM. An endoscopic method for thermal and chemical stimulation of the human oesophagus. Neurogastroenterology and Motility, 2009 [e-pub]
• Pedersen JB, Larsen JF, Drewes AM, Arveschoug A, Kroustrup JP, Gregersen H.  Weight loss after gastric banding is associated with pouch pressure and not pouch emptying rate. Obesity Surgery 2009;19(7):850-855                                                                                                                        
• Pryseley A, Ledent EY, Drewes AM, Staahl C, Olesen AE, Arendt-Nielsen-L. Applying concepts of generalizability theory on data from experimental pain studies to investigate reliabiliry. Basic Clin Pharmacol Toxicol 2009;105(2):105-12
• Sami S, Gaihede M, Nielsen LG, Drewes AM. Early static pressure-related evoked brain potentials indications of central middle ear pressure control in humans.  Otology & neurotology 2009;30(5):649-656
• Staahl C, Olesen AE, Andresen T, Arendt-Nielsen L, Drewes AM. Assessing analgesic actions of opioids by experimental pain models in healthy volunteers - an updated review. Br J Clin Pharmacol 2009;68(3):1391-407
• Staahl C, Olesen AE, Andresen T, Arendt-Nielsen L, Drewes AM. Assessing efficacy of non-opioid analgesics in experimental pain models in ealthy volunteers: an updated review. Br J Clin Pharmacol 2009; 68(3):322-41
• Yang J, Zhao J, Nakaguchi T, Gregersen H. Biomechanical changes in oxazolone-induced colitis in BALB/C mice. Journal of Biomechanics 2009;42(7):811-817
• Yoshida K, Kurstjens GA, Hennings K. Experimental validation of the nerve conduction velocity selective recording technique using a multi-contact cuff electrode. Med Eng Phys 2009;31(10):1261-70
• Zhao JB, Liao D, McMahon B, O'Donovan D, Schiretz R, Heninrich R, Gregersen H. Functional luminal imaging probe geometric and histomorphologic analysis of abdominal wall wound induced by different trocars in pigs. Surgical Endoscopy 2009;23(5):1004-1012
• Zhao JB, Nakaguchi T, Gregersen H. Biomechanical and histomorphometric colon remodelling in STZ-induced diabetic rats. Digestive Diseases and Sciences 2009;54(8):1636-1642
• Zhang HJ, Li P, Zhao J, Zhao SP, Luo YH, Sha H, Guo JZ, Liu H, Li KM. Renal protective effect of Tangshen Formula in rats with diabetic nephropathy. Journal of Beijing University of Traditional Chinese Medicine. 2009; 32 (4): 244-248 (Chinese)
• Zhang HJ, Li P, Zhao J, Zhao SP, Yan MH, Luo YH, Liu H, Li KM, Yang LP, Guo JZ. Effect of Tangshen Formula on expression of TGF-β1 and MMP-9 of renal tissue in STZ-induced diabetic nephropathy rats. Chinese Journal of Integrated Traditional and Western Nephropathy. 2009; 10 (4): 290-294 (Chinese)

PhD Thesis:

• Anne Estrup Olesen. The Analgesic Profiles of Opioids in Human Experimental Pain Models. Aalborg, Denmark
• Christina Brock. A Novel Multimodal Model to Evoke and Modulate Human experimental Rectal Pain

Letter/comments/debate

• Drewes AM, Gregersen H. New technologies in gastrointestinal research. World Journal of Gastroenterology 2009;15(2):129-130

Posters:

• Brock C, Olesen SS, Arendt-Nielsen L, Drewes AM. Real time source reconstruction of the cingilate activity to rectal pain: Mechanisms behind activation of the inhibitory pathways. Neurogastroenterology and Motility 2009; 2009 Aug 27-30; Chicago, USA
• Chen P, Zhao J, Gregersen H. Immunohistochemical investigating advanced glycation end-product and its receptor expression in STZ-induced diabetic rat intestine. 45th EASD Annual Meeting; 2009 sep 30; Vienna Austria
• Frøkjær JB, Søfteland E, Graversen C, Dimcevski G, Egsgaard LL, Arendt-Nielsen L, Drewes AM. Altered neuronal processing of gut pain in diabetes patients with gastrointestinal symptoms.  Neurogastroenterology and Motility 2009;2009 Aug 27-30, Chicago, USA
• Frøkjær JB, Egsgaard LL, Graversen C, Søfteland E, Dimcevski G, Drewes AM. Central neuroplastic reorganisation of gastrointestinal pain processing in diabetic autonomic neuropathy. Gastro; 2009 Nov 21-25; London, England
• Frøkjær JB, Søfteland E, Graversen C, Dimcevski G, Egsgaard LL, Drewes AM. Changes in evoked brain potentials to gut stimulation in diabetes patients with gastrointestinal symptoms. Gastro; 2009 Nov 21-25; London, England
• Gregersen H, Gravesen FH, Olesen SS, Drewes AM, McMahon BP. New high-resolution functional luminal imaging system for the oesophago-gastric junction. Gastro; 2009 Nov 21-25; London, England
• Graversen C, Brock C, Farina D, Drewes AM. Automatic classification of EEG responses to find biomarkers for visceral pain. Neurogastroenterology and Motility 2009; 2009 Aug 27-30; Chicago, USA
• Hoff DA, Gregersen H, Ødegaard S, Hatlebakk JG. Sensation elicited during distension in the esophagus in patients with functional chest pain in caused by mechanical factors rather than by mucosal ischemia. Gastro; 2009 Nov 21-25; London, England
• Krarup AL, Drewes AM. Eosinophilic oesophagitis: A multimodal sensory description. PhD Day; 2009 Jan 16; Aarhus, Denmark
• Krarup AL, Villadsen GE, Funch-Jensen P, Drewes AM, Olesen SS. Eosinophilic oesophagitis: does reflux play a role? Gastro; 2009 Nov 21-25; London, England
• Krarup AL, Drewes AM, Funch-Jensen P. Experimental hypoalgesia in patients with Barretts oesophagus: A biomarker of peripheral neuropathy? Gastro; 2009 Nov 21-25, London, England
• Lelic D, Brokjær A, Hennings K, Drewes AM. Clustering of exogenous pain evoked brain activity; finding common brain sources within groups. Neurogastroenterology and Motility 2009; 2009 Aug 27-30; Chicago, USA
• Liao D, Gravesen F, Villadsen GE, Gregersen H. Impaired esophageal smooth muscle contractility and elasticity in patients with systemic slerosis. Digestive Disease Week 2009; 2009 May 29-Jun 4; Chicago, USA
• Olesen SS, Olesen AE, Gravesen F, Poulsen JL, Funch-Jensen P, Gregersen H, Drewes AM. A new method for thermal stimulation of the human esophagus. Neurogastroenterology and Motility; 2009 Aug 27-30; Chicago, USA
• Olesen SS, Frøkjær JB, Krarup AL, Drewes AM. Pain mechanisms in chronic pancreatitis: Evidence of altered cerebral pain processing. Gastro; 2009 Nov 21-25; London, England
• Zhao J, Chen P, Gregersen H. Intestinal motility and glycation end-products are changed in STZ-induced type 1 diabetic rats. Neurogastroenterology and Motility 2009; 2009 Aug 27-30, Chicago, USA
• Zhao J, Chen P, Yang J, Gregersen H. Jejunal motility in goto-kakizaki (GK) diabetic type 2 rats in vitro. Neurogastroenterology and Motility 2009; 2009 Aug 27-30; Chicago, USA
• Zhao J, Gregersen H. The motility of jejunum and ileum is changed in STZ-induced diabetic rats in vitro. 45th EASD Annual Meeting; 2009 Sep 30; Vienna, Austria.