2007

Publications:

• Arendt-Nielsen L, Curatolo M, Drewes A. Human experimental pain models in drug development: Translational pain research. Current Opinion in Investigational Drugs 2007;8(1):41-53. 
• Arendt-Nielsen L, Frøkjær JB, Staahl C, Graven-Nielsen T, Huggins JP, Smart TS, Drewes AM. The effects of gabapentin on experimental somatic pain and temporal summation. Reg Anesth Pain Med 2007;32:382-8. 
• Arendt-Nielsen L, Schipper K-P, Dimcevski G, Sumikura H, Krarup AL, Giamberardino MA, Drewes AM. Viscero-somatic reflexes in referred pain areas evoked by capsaicin stimulation of the human gut. European Journal of Pain 2007 Oct 29; [Epub ahead of print] 
• Aymen A, Gilja OH, Matre K, Hausken T, Gregersen H. Strain estimation of antral contractions by ultrasound strain rate imaging. Influence of Erythromycin. 2007. 
• Beaumont H, Bergman JJ, Pouw RE, Gondrie JJ, Sondermeijer C, Gregersen H, et al. Preservation of the functional integrity of the distal esophagus after circumferential ablation of Barret's esophagus. 2007. 
• Brinkert W, Dimcevski G, Arendt-Nielsen L, Drewes AM, Wilder-Smith OHG. Dysmenorrhoea is associated with hypersensitivity in the sigmoid colon and rectum. Pain 2007;132(Suppl 1):S46-S51. 
• Dimcevski G, Sami SAK, Funch-Jensen P, Le Pera D, Valeriani M, Arendt-Nielsen L, Drewes AM. Pain in chronic pancreatitis: The role of reorganization in the central nervous system. Gastroenterology 2007;132(4):1546-56. 
• Dimcevski G, Staahl C, Andersen SD, Thorsgaard N, Funch-Jensen P, Arendt-Nielsen L, Drewes AM. Assessment of experimental pain from skin, muscle, and esophagus in patients with chronic pancreatitis. Pancreas 2007;35(1):22-9. 
• Donghua L, Gregersen H. A new method for evaluation of human oesophageal muscle contraction properties in vivo: Force-length relations in oesophagus subjected to different mechanical stimulus. Neurogastroenterology and Motility 2007;19:50. 
• Eisenberg E, Staahl C, Drewes AM, Arendt-Nielsen L.Managing pain in chronic pancreatitis: therapeutic value of opioid treatment.J Pain Palliat Care Pharmacother. 2007;21:63-5. 
• Ernst A, Jacobsen B, Ostergaard M, Okkels H, Andersen V, Dagiliene E, Pedersen IS, Thorsgaard N, Drewes AM, Krarup HB. Mutations in CARD15 and smoking confer susceptibility to Crohn's disease in the Danish population. Scand J Gastroenterol 2007 Dec;42(12):1445-51. 
• Frokjaer JB, Liao D, Steffensen E, Dimcevski G, Bergmann A, Drewes AM, Gregersen H. Geometric and mechanosensory properties of the sigmoid colon evaluated with magnetic resonance imaging. Neurogastroenterol Motil. 2007 Apr;19(4):253-62. 
• Frøkjær JB, Andersen SD, Ejskaer N, Funch-Jensen P, Arendt-Nielsen L, Gregersen H, Drewes AM. Gut sensations in diabetic autonomic neuropathy. Pain 2007 Oct;131(3):320-9. 
• Frøkjær JB, Andersen SD, Ejskjaer N, Funch-Jensen P, Drewes AM, Gregersen H. Impaired contractility and remodeling of the upper gastrointestinal tract in diabetes mellitus type-1. World Journal of Gastroenterology 2007 Sep 28;13(36):4881-90. 
• Gaihede M, Liao D, Gregersen H. In vivo areal modulus of elasticity estimation of the human tympanic membrane system: modelling of middle ear mechanical function in normal young and aged ears. Phys Med Biol. 2007 Feb 7;52(3):803-14. Epub 2007 Jan 16. 
• Gilja OH, Hatlebakk JG, Odegaard S, Berstad A, Viola I, Giertsen C, Hausken T, Gregersen H. Advanced imaging and visualization in gastrointestinal disorders. World J Gastroenterol. 2007 Mar 7;13(9):1408-21. Review. 
• Gregersen H, Kwiatek MA, Schwizer W, Tutuian R. Contribution of sensitivity, volume and tone to visceral perception in the upper gastrointestinal tract in man: emphasis on testing. Neurogastroenterol Motil. 2007 Jan;19(1 Suppl):47-61. Review. 
• Gregersen H, Liao D, Pedersen J, Drewes AM. A new method for evaluation of intestinal muscle contraction properties: studies in normal subjects and in patients with systemic sclerosis. Neurogastroenterol Motil. 2007 Jan;19(1):11-9. 
• Gregersen H, Zhao J, Lu X, Zhou J, Falk E. Remodelling of the zero-stress state and residual strains in apoE-deficient mouse aorta. Biorheology 2007;44(2):75-89. 
• Guo BY, Liao DH, Li XY, Zeng YJ, Yang QH. Age and gender related changes in biomechanical properties of healthy human costal cartilage. Clinical Biomechanics 2007;22(3):292-7. 
• Krarup AL, Gratkowski M, Dimcevski G, Drewes AM. Is the pain in chronic pancreatitis of neuropathic origin? Support from EEG studies during experimental pain. Scand J Gastroenterol 2007;42:30. 
• Liao D, Frøkjær JB, Brock C, Andersen SD, Drewes AM, Gregersen H. Heat Transfer Properties Indication of Segmental Blood Flow Changes during Distension. Neurogastroenterol Motil 2007 Nov 14; [Epub ahead of print] 
• Liao D, Zhao J, Yang J, Gregersen H. The oesophageal zero-stress state and mucosal folding from a GIOME perspective. World J Gastroenterol 2007 March 7; 13(9): 1347-1351. 
• Liu Y, Dang C, Garcia M, Gregersen H, Kassab GS. Surrounding tissues affect the passive mechanics of the vessel wall: theory and experiment. American Journal of Physiology-Heart and Circulatory Physiology 2007;293(6):H3290-H3300. 
• McMahon BP, Frøkjær JB, Kunwald P, Liao DH, Funch-Jensen P, Drewes AM, Gregersen H. The functional lumen imaging probe (FLIP) for evaluation of the esophagogastric junction. American Journal of Physiology-Gastrointestinal and Liver Physiology 2007;292(1):G377-G384. 
• McMahon BP, Odie KD, Moloney KW, Gregersen H. Computation of flow through the oesophagogastric junction. World J Gastroenterol. 2007 Mar 7;13 9): 1360-4. Review. 
• Munk EM, Drewes AM, Gorst-Rasmussen A, Funch-Jensen P, Gregersen H, Norgard B. Risk of Gastrointestinal Cancer in Patients with Unexplained Chest/Epigastric Pain and Normal Upper Endoscopy: A Danish 10-Year Follow-up Study. Dig Dis Sci. 2007 Jul;52(7):1730-7. Epub 2007 Mar 28. 
• Munk EM, Drewes AM, Gorst-Rasmussen A, Gregersen H, Funch-Jensen P, Norgard B. Risk of peptic ulcer, oesophagitis, pancreatitis or gallstone in patients with unexplained chest/epigastric pain and normal upper endoscopy: a 10-year Danish cohort study. Aliment Pharmacol Ther. 2007 May 15;25(10):1203-10. 
• Olesen AE, Staahl C, Ali Z, Drewes AM, Arendt-Nielsen L. Effects of paracetamol combined with dextromethorphan in human experimental muscle and skin pain. Basic & Clinical Pharmacology & Toxicology 2007;101(3):172-6. 
• Pedersen LG, Zhao J, Yang J, Thomsen PD, Gregersen H, Hasenkam JM, Smerup M, Pedersen HD, Olsen LH. Increased expression of endothelin B receptor in static stretch exposed porcine mitral valve leaflets. Res Vet Sci 2007;82(2):232-8. 
• Reddy H, Staahl C, Arendt-Nielsen L, Gregersen H, Drewes AM, Funch-Jensen P. Sensory and biomechanical properties of the esophagus in non-erosive reflux disease. Scand J Gastroenterol. 2007 Apr;42(4):432-40. 
• Riley J, Eisenberg E, Müller-Schwefe G, Drewes AM, Arendt-Nielsen A. Oxycodone: a review of its use in the management of pain. Curr Med Res Opin 2007; Nov 23; [Epub ahead of print] 
• Riley J, Eisenberg E, Müller-Schwefe G, Drewes AM, Arendt-Nielsen A. Oxycodone: a review of its use in the management of pain. Curr Med Res Opin 2007; Nov 23; [Epub ahead of print] 
• Sami S, Gaihede M, Nielsen LG, Drewes AM. Dynamic versus static pressure evoked potentials. Indications of central middle ear pressure control in humans. In Huber A, Eiber A (Eds.) Middle Ear Mechanics in Research and Otology – Proceedings of the 4th International Symposium. World Scientific Publishing Co. Pte. Ltd., Singapore, 2007, pp36-45. 
• Sami SAK, Gaihede M, Kunwald P, Drewes AM. Design of a static pressure stimulation system for neurophysiological investigation of human middle ear function. Measurement Science & Technology 2007 Aug;18(8):N65-N69. 
• Sifrim D, Mittal R, Fass R, Smout A, Castell D, Tack J, Gregersen H. Review article: acidity and volume of the refluxate in the genesis of gastro-oesophageal reflux disease symptoms. Alimentary Pharmacology & Therapeutics 2007;25(9):1003-15. 
• Sifrim D, Mittal R, Fass R, Smout A, Castell D, Tack J, Gregersen H. Acidity and volume of the refluxate in the genesis of gastro-oesophageal reflux disease symptoms. Alimentary Pharmacology & Therapeutics 2007;25(9):1003-17. 
• Staahl C, Dimcevski G, Andersen SD, Thorsgaard N, Christrup LL, Arendt-Nielsen L, Drewes AM. Differential effect of opioids in patients with chronic pancreatitis: An experimental pain study. Scand J Gastroenterol 2007;42(3):383-90. 
• Storkholm JH , Zhao J, Villadsen GE, Hager H, Jensen SL, Gregersen H. Biomechanical remodeling of the chronically obstructed guinea-pig small intestine. 2007 Feb;52(2):336-46. Epub 2007 Jan 12. [Epub ahead of print] 
• Storkholm JH, Zhao J, Villadsen GE, Gregersen H. Spontaneous and Bolus-induced Motility in the Chronically Obstructed Guinea-Pig Small Intestine In vitro. Dig Dis Sci. 2007 Jun 12; [Epub ahead of print] ) 
• Zhao J, Andreasen JJ, Yang J, Rasmussen BS, Liao D, Gregersen H. Manual pressure distension of the human saphenous vein changes its biomechanical properties-implication for coronary artery bypass grafting. J Biomech 2007;40(10):2268-76. 
• Zhao J, Chen X, Yang J, Liao D, Gregersen H. Opening angle and residual strain in a three-layered model of pig oesophagus. J Biomech. 2007 May 19; [Epub ahead of print] 
• Zhao J, Gregersen H. Disorders of biomechanical properties and motility of small intestine in diabetes (review). Recent Res. Devel. Biomechanics, 3 (2007, in press). 
• Zhao J, Jorgensen CS, Liao D, Gregersen H. Dimensions and circumferential stress-strain relation in the porcine esophagus in vitro determined by combined impedance planimetry and high-frequency ultrasound. Dig Dis Sci. 2007 May;52(5):1338-44. Epub 2007 Mar 14. 
• Zhao JB, Chen XD, Gregersen H. The villi contribute to the mechanics in the guinea pig small intestine. FASEB J 2007;21(6):A1326. 
• Zhao JB, Gregersen H. Biomechanical and morphometric colon remodelling in STZ-induced diabetic rats. FASEB J 2007;21(6):A1133. 
• Zhao JB, Liao DH, Gregersen H. Biomechanical and histomorphometric esophageal remodeling in type 2 diabetic GK rats. J Diabetes Complications 2007;21(1):34-40. 
• Zhao JB, Liao DH, Yang J, Gregersen H. Effect of partial obstruction on the contraction of guinea pig jejunum. FASEB J 2007;21(6):A1326. 

Ph.D. thesis:

PhD thesis: Camilla Staahl. The analgesic and pharmacokinetic profiles of opioids in a multi-modal and tissue differentiated experimental pain model. Aalborg Universitet 2007 
PhD thesis: Estrid Muff Munk. Clinical epidemiological studies in patients with unexplained chest and/or epigastric pain. Aarhus Universitet 2007 
PhD thesis: Georg Dimcevski. The characteristics of pain in patients with chronic pancreatitis. A study based on experimental pain stimulations of the gastrointestinal tract. Aalborg Universitet 2007 
PhD thesis: Hiroyuki Sumikura. Role of inflammation for secondary heat hyperalgesia detected by radiant heat stimuli. Aalborg Universitet 2007                                                                                                                                                                           PhD thesis: Parisa Gazerani. The Study of Human Models of trigeminal Pain and Sensitization Induced by Cutaneous Injections of Capsaicin and Glutamate. Aalborg Universitet 2007. Aalborg Universitet 2007 
 

Conference presentations:

• Zhao JB, Chen XD, Gregersen H, (2007) Evaluation of mucosal villous contribution to the mechanics in the guinea pig small intestine. 2007 Experimental Biology meeting abstracts [on CD-ROM], Abstract #935.1 
• Zhao JB, Chen XD, Yang J, Liao DH, Gregersen H, (2007) Opening angle and residual strain in a three-layered model of pig esophagus. 2007 Experimental Biology meeting abstracts [on CD-ROM], Abstract #902.2 
• Zhao JB, Nakaguchi T, Gregersen H, (2007) Biomechanical and morphometric colon remodelling in STZ-induced diabetic rats. 2007 Experimental Biology meeting abstracts [on CD-ROM], Abstract #866.8 
• Zhao JB, Yang J, Gregersen H, (2007) Effect of partial obstruction on the contraction of guinea pig jejunum. 2007 Experimental Biology meeting abstracts [on CD-ROM], Abstract #935.2
   

Participition in congresses and symposias:

• Zhao JB: 2007 Experimental Biology meeting. 28 April – 3 May 2007, Washington DC, USA